C10orf12
WebC10orf12 and C17orf96 interactions revealed that these proteins may be mutually exclusive PRC2 subunits that fail to interact with eachotheror withJARID2andAEBP2.C10orf12,in … WebC10ORF12 and C17ORF96 also interacted with MTF2 ( 609882 ), which binds histone H3 (see 602810) trimethylated on lys36 (H3K36me3), and with the ubiquitin-specific protease USP7 ( 602519 ). Chromatin immunoprecipitation analysis showed genomewide enrichment domains for C10ORF12 and C17ORF96 that closely matched those of EZH2 and …
C10orf12
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WebC10ORF12 also antagonizes Jarid2, which is an auxiliary factor of the PRC2.2 subcomplex, to promote increased H3K27me3 levels in HeLa cells. Moreover, C10ORF12 alters the substrate preference of PRC2. WebC10ORF12 was recently identi fi ed as a novel PRC2 interactor. Here, we show that C10ORF12 speci fi cally interacts with PRC... View Ligand-induced activation of ERK1/2 signaling by...
WebJan 13, 2014 · C10orf12, in addition, shows a strong and unexpected association with components of the EHMT1/2 complex, thus potentially connecting PRC2 to another … WebThis polyclonal antibody is raised against a large isoform (isoform 3; a splice variant), which associates with the PRC2 complex through its C-terminal region. Its nuclear localization signal is reported to be in amino acids 339-345 and it reacts with nuclear receptors via amino acids 53-57. (Ref.: Conway, E., et al. (2024). Mol.
WebGene Symbol: C10orf12; Aliases: Not Available: RefSeq: Not Available: Ensembl: ENSCAFG00000031956 : Entrez: 0 : UniGene: Not Available: Why PrimePCR? PrimePCR Lookup Tool. Design and Validation of Real-Time PCR Primers-test ® Pathway Curation ... High titers of recombinant baculovirus carrying the PRC2 complex and C10ORF12 (> 109 viral particles/mL) were obtained using the Bac-to-Bac baculovirus expression system (Invitrogen, Carlsbad, CA, USA). The titer of each baculovirus stock was determined using the anti-baculovirus envelope gp64 antibody. … See more cDNAs for C10ORF12 (UniProtKB entry sequence A0PJI9) and the PRC2 subunits EZH2, EED, SUZ12, RbAp48, and AEBP2 (UniProtKB entry isoform sequences Q15910–1, … See more The average molecular mass of the C10ORF12-PRC2 complex was determined on a DAWN HELEOS-II instrument (Wyatt) connected in tandem to a high-performance liquid chromatography system (Agilent). A … See more The HMTase activity of PRC2 was measured using Perkin Elmer AlphaLISA kits [56]. Enzymatic reactions were promoted by incubating 10 nM PRC2 with assay buffer (50 mM Tris-HCl, pH 8.0; 50 mM NaCl; 1 mM … See more Protein copurification pulldown assays were performed following previously described protocols [55]. In brief, 40 mL of Sf9 cells was co … See more
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WebLOC103812005 chromosome unknown open reading frame, human C10orf12 [ (rifleman)] Gene ID: 103812005, updated on 12-Mar-2024. Summary Other designations. uncharacterized protein C10orf12 homolog nav consulting pricingWebC10orf12 from Biorbyt. Product Specs; Item C10orf12; Company Biorbyt; Catalog Number orb528893; This product is no longer available on Biocompare. Biocompare is the leading resource for up-to-date product information, product reviews, and new technologies for life scientists. About Biocompare market harborough kitchen shopWebC10ORF12 significantly enhances the histone methyltransferase activity of PRC2 in vitro and dramatically increases the total H3K27me3 levels in HeLa cells. C10ORF12 also … market harborough leicestershire englandWebThe C10orf12 Antibody from Novus Biologicals is a rabbit polyclonal antibody to C10orf12. This antibody reacts with human. The C10orf12 Antibody has been validated for the … market harborough leisure centre classesWebReciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification. Alekseyenko AA, Gorchakov AA, Kharchenko PV, Kuroda MI Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2488-93. doi: 10.1073/pnas.1400648111. Epub 2014 Feb 3. PubMed Article Plasmids from Article ... nav consulting usaWebZestimate® Home Value: $1,881,700. 8412 10th Ave, Brooklyn, NY is a single family home that contains 2,400 sq ft and was built in 1920. It contains 4 bedrooms and 4 bathrooms. … nav consulting oakbrookWebGene Aliases: C10orf12; KIAA1795; LCOR; MLR2 UniProt ID: (Human) Q96JN0 Entrez Gene ID: (Human) 84458 Molecular Function: DNA-binding transcription factor Function (s) negative regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter Process (es) navcontroller navigate with arguments