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Glyoxalase family protein

WebProtein family (Pfam) PF00903. Domain description: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Occurring in: VOC domain-containing protein; InterPro annotations. IPR029068. Domain description: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WebApr 6, 2024 · The search for glyoxalase proteins from prokaryotes to eukaryotes has indicated that the glyoxalase family expanded exclusively in plant systems (Fig. 2a,b). This expansion probably resulted from …

Glyoxalase system - Wikipedia

WebThese proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. Web3.8.3.9 Glyoxalase I. Glyoxalase I (Glx I) catalyzes the reaction between methylglyoxal and glutathione, forming S -lactoylglutathione as the product. Human Glx I contains 183 amino acids, and in its monomeric form, it folds into two domains and an isolated N-terminal helix. Each domain is composed of a four-stranded β sheet flanked by two α ... gyms burleigh heads https://recyclellite.com

Reassessing plant glyoxalases: large family and expanding …

WebOct 25, 2024 · Conserved Protein Domain Familyglyox_I. ? Lactoylglutathione lyase is also known as aldoketomutase and glyoxalase I. Glyoxylase I is a homodimer in many species. In some eukaryotes, including yeasts and plants, the orthologous protein carries a tandem duplication, is twice as long, and hits this model twice. WebNov 12, 2024 · The Arabidopsis genome annotation include 11 glyoxalase I (GLXI) genes, all encoding for protein members of the vicinal oxygen chelate (VOC) superfamily. The biochemical properties and physiological … WebFamily and domain databases. CDD. cd07237 BphC1-RGP6_C_like 1 hit; cd07252 BphC1-RGP6_N_like 1 hit; Gene3D. 3.10.180.10 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, … gyms bury st edmunds

Q81F54 - UniProt

Category:InterPro - ebi.ac.uk

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Glyoxalase family protein

Analysis of the interactome of the Ser/Thr Protein Phosphatase …

WebMar 6, 2007 · Family and domain databases. CDD. cd07233 GlxI_Zn 1 hit; Gene3D. 3.10.180.10 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 1 hit; InterPro. View protein in InterPro; IPR029068 Glyas_Bleomycin-R_OHBP_Dase; ... SSF54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 1 hit;

Glyoxalase family protein

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WebInterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool. WebMay 6, 2024 · In the cassava genome database (Manihot esculenta V6.1), GLYI family genes in cassava were searched and identified in multiple ways, by searching the keywords glyoxalase, PF00903, PF12681 and PF18029, and BLAST based on the known GLYI protein sequences in Arabidopsis thaliana. The identified genes were named in …

WebThe glyoxalase system is a ubiquitous enzymatic network which plays important roles in biological life. It consists of glyoxalase 1 (GLO1), glyoxalase 2 (GLO2), and reduced glutathione (GSH), which perform an essential metabolic function in cells by detoxifying methylglyoxal (MG) and other endogenous harmful metabolites into non-toxic d-lactate. WebGlyoxalase family protein. Kind. protein. Organism. Bacillus cereus (strain ATCC 14579 / DSM 31) Protein. Name. UniProt ID. Glyoxalase family protein.

WebFeb 10, 2024 · The enzyme involved is glyoxalase III, also known as DJ-1 protein due to its high sequence similarity with human DJ-1 protein (HsDJ-1). In humans, DJ-1 proteins are associated with early onset of Parkinson disease and it was only later that the presence of glyoxalase III activity was reported in such proteins [ 11 ]. WebGlyoxalase family protein Kind protein Organism Bacillus cereus (strain ATCC 14579 / DSM 31) Protein. Name UniProt ID; Glyoxalase family protein: Q81F54: Details: Drug Relations Drug Relations. DrugBank ID Name Drug group Pharmacological action? Actions Details; DB01942: Formic acid: experimental, investigational:

WebGlyoxalase family protein Imported. Gene names. Ordered locus names. BCAH187_A3046 Imported. Organism names. Organism. Bacillus cereus (strain AH187) Imported. Taxonomic identifier. 405534 NCBI. ... SSF54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 1 hit; MobiDB.

WebAccordingly, it can be highly advantageous to perform the protein purification and the Glo1 activity assays in MOPS buffers with low salt concentrations instead of phosphate buffers … gyms burleigh watersWebGlyoxalase I that uses Zn (++) as cofactor. This family includes eukaryotic glyoxalase I that prefers the divalent cation zinc as cofactor. Glyoxalase I (also known as lactoylglutathione lyase; EC 4.4.1.5) is part of the glyoxalase system, a two-step system for detoxifying methylglyoxal, a side product of glycolysis. gyms by my houseWebSep 2, 2024 · This review presents a thorough overview of the literature surrounding this diverse enzyme class. Although extensive literature exists for some members of this family (e.g., GLO1), little is known about the physiological role of glyoxalase domain-containing protein 4 (GLOD4) and 5 (GLOD5), paving the way for exciting avenues for future … gyms by 3520 south dakota ave neWebMar 17, 2016 · Background. Protein Phosphatase 1 (PP1) is an enzyme essential to cell viability in the malaria parasite Plasmodium falciparum (Pf). The activity of PP1 is regulated by the binding of regulatory subunits, of which there are up to 200 in humans, but only 3 have been so far reported for the parasite. gyms by meWebApr 16, 2016 · The present study identifies the largest family of glyoxalase proteins to date with 41 GmGLYI and 23 GmGLYII members in soybean. Detailed analysis of GmGLYI and GmGLYII genes strongly indicates the genome-wide segmental and tandem duplication of the glyoxalase members. ... Glyoxalase protein sequences from various plant species … b.p. collectibles diecast \u0026 toysWebJul 15, 2024 · The glyoxalase pathway plays a vital role in the chemical detoxification of methylglyoxal (MG) in biological systems. Our previous study suggested that OsGLYI3 may be effective in seed natural aging. In this study, the rice OsGLYI3 gene was cloned and characterized as specifically expressed in the seed. The accelerated aging (AA) … bp columbus ncWebGlyoxalase family protein. Status. UniProtKB unreviewed (TrEMBL) Organism. Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB … gyms by 76082