2024 Hotair overexpression

Hotair overexpression

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August undefined, 2024

WebMay 21, 2015 · Effects of HOTAIR overexpression differed between cell lines. Whereas VM-CUB1 cells acquired the expected phenotype with increased proliferation, clonogenicity, …

Overexpression of HOTAIR leads to radioresistance of human …

WebOct 24, 2024 · HOTAIR overexpression promoted tumor growth in mice bearing HeLa and exposed to radiation. Radiotherapy might inhibit cervical cancer cell growth through HOTAIR/HIF-1α pathway. HOTAIR was known to enhance radioresistance in several cancers. However, the function of HOTAIR on radioresistance involving the regulation of HIF-1α in … WebJun 1, 2024 · Results. A negative correlation between adipose tissue HOTAIR expression (arm or abdominal subcutaneous fat depots) and regional adiposity under the status of severe obesity or uraemia was observed.HOTAIR overexpression using human immortalized abdominal preadipocytes further revealed its anti-adipogenic effects. Integrative analysis … definition of a atomic number

lncRNA HOTAIR overexpression induced downregulation of c-Met signaling ...

WebTo verify the above observation, HOTAIR plasmid was conducted, as shown in Fig. 2B, overexpression of HOTAIR significantly increased CD11b expression in HL-60 cells, indicating an enhancement of myeloid differentiation, but not in NB4, U937, and THP-1 cell lines. Interestingly, we overexpressed HOTAIR in HL-60 cells but without ATRA treatment ... WebMay 20, 2024 · Overexpression of HOTAIR in HASMCs was confirmed using qRT-PCR (Fig. 2a). miR-126 expression was significantly reduced in the HOTAIR overexpressed HASMCs compared to the control group (Fig. 2a). As shown in Fig. 2 b and c, HOTAIR overexpression markedly attenuated Pi-induced calcium deposition and calcium nodules formation in … WebMar 30, 2024 · Nevertheless, overexpression of FUS can partially reverse the effect of overexpression of HOTAIR on Cyclin D1 and p21, while overexpression of SIRT3 can … definition of ab

Overexpression of HOTAIR attenuates Pi-induced vascular

Inducible lncRNA transgenic mice reveal continual role of HOTAIR …

WebDec 6, 2024 · HOTAIR overexpression enhanced, whereas its knockdown reduced, cell proliferation, cachexia-associated pro-inflammatory cytokine expression, and muscle atrophy. Cachexia-associated symptoms were ameliorated in mice bearing Hotair-knockdown bladder tumors undergoing cisplatin treatment. We demonstrate for the first … WebApr 3, 2024 · The transport of multivesicular bodies (MVBs) after overexpression of HOTAIR was detected by transmission electron microscopy and confocal microscopy analysis of cluster determinant 63 (CD63) with synaptosome associated protein 23 (SNAP23). The mechanism of HOTAIR’s regulation of Ras-related protein Rab-35 (RAB35), vesicle … felica port software 4.3.1 down roadWebNov 28, 2024 · To create the A783U mutant HOTAIR overexpression plasmid, staggered QuikChange oligos AG66/AG67 were used to generate the A783U mutation in pTRE3G-HOTAIR using the QuikChange Site Directed Mutagenesis Kit (Agilent 200519) to generate pTRE3G-A783U_HOTAIR. A 1.6 Kb fragment of A783U mutant HOTAIR was amplified with … definition of a baby

"WebHOTAIR was the first lncRNA to be identified for its role in metastasis. Overexpression of HOTAIR is associated with metastasis in multiple cancers, including breast, pancreatic, lung, hepatocellular carcinoma, and colorectal [19,154–157]. " - Hotair overexpression

Hotair overexpression

Long non-coding RNA HOTAIR promotes exosome secretion by regulating …

WebApr 12, 2024 · Carolina BalloonFest is the second-oldest hot air balloon festival in the world and been running for nearly 50 years. The Statesville -based festival brings in close to … WebFeb 7, 2024 · Downregulation of HOTAIR was detected in osteosarcoma, which predicted poor prognosis of patients with osteosarcoma. Moreover, cell migration, invasion, and proliferation were suppressed by HOTAIR overexpression in osteosarcoma. Furthermore, LPR5 was a direct target of HOTAIR, which was upregulated in osteosarcoma.

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WebOverexpression of HOTAIR is associated with metastasis in multiple cancers, including breast, pancreatic, lung, hepatocellular carcinoma, and colorectal [19,154–157]. HOTAIR … WebOct 24, 2024 · HOTAIR overexpression promoted tumor growth in mice bearing HeLa and exposed to radiation. Radiotherapy might inhibit cervical cancer cell growth through …

WebMar 30, 2024 · BisPhenol A, diethylstilbesterol, and IRF1 promote the overexpression of HOTAIR by binding to the corresponding gene promoter elements. Bisphenol A and diethylstilbesterol independently interact with estrogen receptors in the cytoplasm, translocate into the nucleus, associate with the methyl transferases MLL1 and MLL3, bind … WebNational Center for Biotechnology Information

WebApr 15, 2010 · Conversely, overexpression of EZH2 in H16N2 breast cells is known to promote matrix invasion 12, but concomitant depletion of endogenous HOTAIR in large … WebSep 3, 2024 · The overexpression of HOTAIR was found to induce nucleus pulposus (NP) cell senescence, apoptosis, and extracellular matrix (ECM) degradation. HOTAIR silencing by RNA interference in NP cells prevented interleukin-1β-induced NP cell senescence, apoptosis, and ECM degradation. Furthermore, we found that the Wnt/β-catenin pathway …

WebJul 11, 2024 · Overexpression of HOTAIR (HOTAIR OE, presented in figures as HOTAIR clone) and its effect on c-Met expression were analyzed and confirmed with confocal …

WebMay 21, 2012 · HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and overexpression is correlated with poor survival for breast, colon and liver ... felica port software 4.3.1 インストールしたいWebNon-coding RNAs are emergent elements from the genome, which do not encode for proteins but have relevant cellular functions impacting almost all the physiological processes occurring in eukaryotic cells. In particular, microRNAs and long non-coding RNAs (lncRNAs) are a new class of small RNAs transcribed from the genome, which modulate … felica standard 非接触icカード rc-s100WebApr 28, 2014 · Furthermore, HOTAIR overexpression promoted the proliferation, migration and invasion of gastric carcinoma cells, while HOTAIR depletion inhibited both cell … definition of a baby girlWebSep 14, 2015 · HOTAIR overexpression is sufficient to activate the ER transcriptional program even under hormone-deprived conditions. Functionally, we found that HOTAIR overexpression increases breast cancer ... felica sony ドライバーWebAlso, overexpression of HOTAIR promoted the migration and invasion ability of lung cancer cells, confirmed by wound healing assay and transwell assay, which was suppressed by overexpression of miR-149-5p. Furthermore, dual-luciferase reporter assay indicated that miR-149-5p could bind both HOTAIR and the 3’UTR of HNRNPA1. felica port software 4.3.1 ダウンロードWebJun 16, 2024 · HOTAIR overexpression has been shown to promote adipogenesis in abdominal adipose stem cells (ASCs) 3 and to prevent adipose differentiation of bone marrow mesenchymal stem cells 7. felica rc s330 windows11WebFeb 6, 2024 · The ability of lncRNA HOTAIR to recruit chromatin-modifying factors has served as a paradigm for lncRNA-mediated repression of target genes. Contrary to … definition of a backdraught