Human ether-à-go-go related gene
Web1 mrt. 2024 · Background. KCNH2 encodes the human ether-à-go-go-related gene potassium channel, which passes the rapid delayed rectifier potassium current. Loss-of … Web25 feb. 2024 · 人类ether-a-go-go相关基因 (human ether-a-go-go-related gene, hERG)编码的快速激活延迟整流钾电流 (IKr) 是心肌细胞动作电位3期复极化的主要电流成分。 药 …
Human ether-à-go-go related gene
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WebThe human Ether-a-go-go Related Gene (hERG) potassium channel plays a central role in regulating cardiac excitability and maintenance of normal cardiac rhythm. … WebMany translated example sentences containing "human ether-a-go-go related gene" – German-English dictionary and search engine for German translations. Look up in …
Web1 okt. 2006 · DOI: 10.1016/J.PHARMTHERA.2006.03.002 Corpus ID: 20636636; Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets … WebTolterodine is a first-line antimuscarinic drug used to treat overactive bladder. Adverse cardiac effects including tachycardia and palpitations have been observed, presumably …
Web8 okt. 2024 · Long QT syndrome (LQTS) is a hereditary disease that predisposes patients to life-threatening cardiac arrhythmias and sudden cardiac death. Our previous study of the … WebAlternate transcripts of the human ether-à-go-go-related gene (hERG1) encode two subunits, hERG 1a and 1b, which form potassium channels regulating cardiac …
Web15 feb. 2024 · Integration of the dynamic hERG (human Ether-à-go-go-Related Gene) model into O’Hara–Rudy (ORd) cardiomyocyte model. A , An action potential (AP; cycle …
Web1 mrt. 2014 · Human ether-à-go-go-related gene gain-of-function mutations N588K and L532P favour reentry by shortening the effective refractory period in combination with a … hen\u0027s-foot 08Web在心肌细胞中,human Ether-a-go-go Related Gene (hERG)编码的钾通道介导一种延迟整流钾电流 (IKr),IKr抑制是药物导致QT间期延长最重要的机制 (图1)。 hERG因其特殊的 … hen\u0027s-foot 0hWeb14 okt. 2012 · hERG的全称是human ether-a-go-go related gene。它是从人的海马神经中分离出来的基因。hERG基因编码形成电压激活延迟内向整流的钾离子通道(Ikr),大量分 … hen\u0027s-foot 0mWebAbstract Human ether-à-go-go-related gene (HERG) is over-expressed in a wide range of human cancers and regulates survival, migration, and apoptosis. The aim of this study … hen\u0027s-foot 0aWeb25 jun. 2013 · The human ether-à-go-go-related gene (hERG) ion channel underlies the fast delayed rectifier current (I Kr) in the heart and is the major contributor to the … hen\\u0027s-foot 0qWeb1 aug. 2002 · Long QT syndrome type 2 (LQT2) is caused by mutations in the human ether-à-go-go related gene (hERG), which encodes the Kv11.1 potassium channel in the heart. hen\u0027s-foot 0gWebhERG (the human Ether-à-go-go-Related Gene),人延迟整流钾离子通道基因,是指基因KCNH2。 该基因编码的蛋白质被称为 K v 11.1,是钾离子通道(英語: potassium ion … hen\\u0027s-foot 0i