Web26 dic 2024 · To determine the role of E2F in MM growth and proliferation, we perturbed E2F1 and DP1 in a panel of MM cell lines that all detectably express both genes (Figure S1 A).Steady-state depletion of E2F1 or DP1 effectively inhibited cell proliferation in MM1.S cell line (Figures 1 A and S1 B) and across 8 different cell lines independent of their genetic … Web20 gen 2024 · Crews and colleagues demonstrate that selective antisense oligonucleotides targeting the plasma cell transcription factor, IRF4, reduce disease burden and myeloma regeneration in human-relevant pre-clinical models. Mechanistically, IRF4 overexpression expands a myeloma progenitor population, while IRF4 inhibition impairs cell survival via …
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WebGet Parts, Repair Help, Manuals and Care Guides for FEFL79JCB Frigidaire Range. View parts like Temperature Sensor and Light Bulb. Web16 lug 2024 · Cell Cultures GmbH (Braunschweig, Germany). KMS-11 (JCRB1179) human MM cell line was purchased from Cell Bank Australia (Sydney, Australia). MM.1S, … family olive practice
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Web(JCRB0034 and JCRB1179), and these cells were maintained in RPMI 1640 medium containing 10% FBS and 100 lg/mL of kanamycin. siRNA Transfection. Cells were … Web21 apr 2024 · Catalogue number: KMS-11, JCRB1179), or Lonza (Basel, Switzerland. Catalogue number: HUVEC, C-2519A), and were acquired between 2003 and 2013. All … Web21 apr 2024 · Catalogue number: KMS-11, JCRB1179), or Lonza (Basel, Switzerland. Catalogue number: HUVEC, C-2519A), and were acquired between 2003 and 2013. All cell lines were confirmed to be negative for mycoplasma (Bionique Testing Laboratories, Inc., Saranac Lake, NY), and cell lines used for in vivo testing were authenticated by short … family old parents