Ly49h gene
Ly49 is a family of membrane C-type lectin-like receptors expressed mainly on NK cells but also on other immune cells (some CD8+ and CD3+ T lymphocytes, intestinal epithelial lymphocytes (IELs), NKT cells, uterine NK cells (uNK) cells, macrophages or dendritic cells). Their primary role is to bind MHC-I … Vedeți mai multe Role in NK cells The function of NK cells is the killing of virally infected or cancerous cells. Therefore, they must have a precisely regulated system of self-cell recognition to prevent the … Vedeți mai multe Inhibitory receptors Inhibitory receptors play a role in the NK cell licensing and are important for recognition … Vedeți mai multe WebAbstract. Stochastic expression is a hallmark of the Ly49 family that encode the main MHC class-I-recognizing receptors of mouse natural killer (NK) cells. This
Ly49h gene
Did you know?
Web21 mar. 2024 · LY9 (Lymphocyte Antigen 9) is a Protein Coding gene. Diseases associated with LY9 include Multisystem Inflammatory Syndrome In Children and … Web31 aug. 2024 · Previous studies have established that the response to mCMV infection is strain-dependent in mice, with susceptibility determined by expression of the Ly49H …
Web4 mai 2001 · Yet, BXD-8 NK cells express allotypic epitopes for all other serologically detectable C57BL/6-derived Ly-49 molecules, including Ly-49D, whose gene is within … WebClone REA241 recognizes mouse lymphocyte antigen 49H (Ly-49H) which is also known as killer cell lectin-like receptor 8, Klra8, or Cmv-1. REA241 does not crossreact with related …
Web14 mar. 2024 · In C57BL/6 mice, a subset of naive Ly49H + NK cells initiate this adaptive response after recognition of the MCMV-encoded glycoprotein m157 (refs. ... Gene ontology (GO) ... WebTarget Information. Ly49H is a member of the C-type lectin Ly-49 multigene family of receptors found on natural killer cells. Ly49H, like Ly49D, lacks the characteristic ITAM …
Web靶标信息 Ly49H is a member of the C-type lectin Ly-49 multigene family of receptors found on natural killer cells. Ly49H, like Ly49D, lacks the characteristic ITAM (immunoreceptor …
Web1 feb. 2005 · Recently, we examined, via microarray analysis, the breadth of gene expression following Ly49D cross-linking (George et al., 1999; ... Ly49D and Ly49H are … high black stiletto bootsWeb18 mar. 2013 · Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain) Crystal structure of the activating Ly49H receptor in complex with m157 … how far is margate from uvongoWeb对巨细胞病毒感染的小鼠和人类nk细胞的研究揭示了与传统nk细胞在功能和表型特征方面的一些显着差异。在小鼠中，在长寿nk细胞池中发现了标记物ly49h，这些细胞可以在病毒 … high black socks with shortsWeb12 iun. 2006 · However, resistance was independent of Ly49H and m157, as NZW mice do not possess a Ly49H gene. Moreover, treatment with an anti-Ly49H antibody, which conferred MCMV susceptibility in C57BL/6 mice, had no effect on viral titers in NZW mice . When MCMV-resistant NZW mice were mated and backcrossed with other MCMV … high black strappy heelsWeb5 iun. 2008 · Following Ly49h, m and w is a cluster of genes first identified in 129 mice: Ly49p 1, pd 1, g 1 and i 1. 15 This region is in turn followed by duplications of Ly49p and … high black teguWeb17 mai 2002 · Moreover, a gene promoting resistance to MCMV infection, Cmv-1 , found in some strains of mice, is expressed by subsets of NK cells and encodes the activating Ly49H receptor (9–12). After exposure to m157 in vitro, Ly49H + NK cells from mice that are resistant to MCMV exhibit an increased ability to lyse target cells and to produce IFN-γ ... high black toiletWebTo show the impact of viral silencing genes in a Ly49H⫹ natural killer gene complex from C57BL/6 mice, they are sus- strain, we compared ⌬m157 with w.t. MCMV and a virus in … high black velvet boots